A train has derailed in north-western Spain, killing at least 35 people and injuring many more, officials in Galicia region have said.
All 13 carriages of the train, which was travelling from Madrid to Ferrol, came off the tracks near the city of Santiago de Compostela.
Images from the scene showed bodies strewn near ruined carriages, and emergency crews searching the wreckage.
Analysts say it is the worst rail accident in Spain in four decades.
Prime Minister Mariano Rajoy convened an emergency ministerial meeting late on Wednesday and is due to visit the scene of the accident on Thursday.
Local authorities have issued an appeal for residents to donate blood to hospitals in the area.
Leader of the regional government Alberto Nunez Feijoo confirmed the death toll but told radio Cadena Ser that it was too early to say what caused the accident.
“There are bodies lying on the railway track. It’s a Dante-esque scene,” he said in comments translated by the AFP news agency.
The BBC’s Tom Burridge in Madrid says Thursday is a local holiday in the region, and many people would have been preparing to celebrate.
Local journalist Francisco Camino said the region was in shock.
“This is a tiny place and nothing happens here, nothing important or tragic,” he told the BBC.
“We were preparing for the celebrations and now this could turn out to be the worst train crash in many years.”
Railway firm Renfe said the train was carrying at least 218 passengers, and came off the tracks on a bend about 3km (two miles) from Santiago de Compostela station.
It was on the express route between Madrid and the ship-building city of Ferrol on the Galician coast.
Images showed dozens of emergency workers crowded around ruined carriages.
Passengers were shown lying on the ground being treated, and there were several bodies near the tracks.